Nowadays, reflex DNA screen in Alpha prenatal software runs screening protocol whit using DNA parts in the plasma of mothers.

The benefit of this test is a low price in comparison with public DNA test and low amount of false positive cases of this test. In REFLEX DNASCREEN, mothers should first be screened by the tests of the first, second or third quarter.

In the event that pregnant mothers recognizes in a high-risk group, a cell free DNA test will automatically introduce to do the test.

Different Cut offs have determined to do the test for different Trisomy.