The calculation of the risk of preeclampsia in Alpha is done by AFP-UE3-HCG and INHIBIN A+PLGF in the second quarter PLGF-PAPP-A and the average of arteriolar pressure is used for the calculation of the risk in the first quarter.

This allows an opportunity for grater oversight of this anomaly and will help in the prophylactic treatment of patients who have a high risk.

By using markers in Quad + PLGF test, the estimate of the risk of preeclampsia,52% detection rate and false positive rate of 5% can be created. If you are using PAPP-A and MAP in the first quarter and adding markers in Quad + PLGF marker in the second trimester, the detection rate to detect the abnormality will be 64%.